Actually, my "not Comment" color selection does not stay (persist), not even among search attempts in the same workspace/project in the same SE session: (1) I bring up the Find and Replace window with the Find in Files tab selected, and go to the Color window to deselect Comment. (2) Click Find to perform my search. (3) Bring up the Find and Replace window again and my "not Comment" color selection is gone (says "Colors: None").
Other attributes of Find and Replace persist in the above example: Active tab, whether to match case or whole words, whether to append to output, etc. But my Color selection doesn't persist.