-- Better C#/WPF support.
-- Working in a file with a .cs extension is almost unusably slow.
-- SlickEdit doesn't deal with the whole .xaml/.xaml.cs situation very well. (Objects declared in the xaml aren't tagged, and you can't find them by trying look them up or looking for references.)
I am switching more and more to VisStudio when working on C#/WPF stuff.
-- Better ATL/COM (C++) support. Tagging is terrible for many ATL constructs.
Completion is non-existent for constructs like CComPtr:
CComPtr<EnvDTE::Windows> pWindows;
pWindows-> // SlickEdit offers nothing...
Same here: using VisStudio more and more just to get IntelliSense.