Agreed 100%. Even within a given project there are times when you want to build against different versions of Python (f.e. when developing a module intended for both Py2 & Py3). It'd be great if the project settings allowed us to configure multiple interpreter configurations, and then potentially build against one, some or even all of them, as part of validation/verification. PyCharm and Komodo both support this to varying extents, and it would be useful if SE could as well.