What platform? 64 bit windows?
One thing to try is to open up a python file, and then in a file manager or terminal go to the configuration directory (location listed in the Help -> About if you're not sure where it is). From there, go to rte, and open up the rteout file. Even if your script isn't being called, there may be some error output in there that can give us an idea of what's happening.
For the Options -> Language Settings -> Scripting Langages -> Python > Live Errors configuration for Python, ensure the default profile selects a profile you want, and it's not set to Auto Detect.
One other thing to check is to see if there are any Live Errors profile overrides in the project you have open. Open up Project -> Project Properties, and go to the Live Errors tab, and see if there are any overrides for Python, and if so if they are referencing the correct profile.
If that doesn't turn up anything, I may need to send you something to enable some logging. I do have some code for turning some of the compile time logging for Live Errors into logging that can be enabled with a setting, but it's not in the v26.0.x yet.