Created a simple "Hello World" C++ app with latest SE27.0.1.x64 (hotfix_se2701_3) on Win10Pro.x64.21H2(19044.1348).
Building and running works fine.
But adding a breakpoint in Main and trying to Debug->Start crashes SE silently. (SE 27.0.0.6 was doing the same, this is why I just installed and tried 27.0.1 unfortunately no luck).
Added vs.exe minidump, my config and the resulted example project to case CAS-74049-NPDZ.