What OS?
What version of SE? (I think 14?)
What language?
What file extension?
I think you mean the "Case-insensitive" checkbox in the Identifiers box of the Tokens tab of the {Some Language} > Color Coding node in Tools|Options, is that right?
I think you mean the "Color inactive code regions (C/C++ Preprocessing, eg. #if 0)" checkbox at the bottom of the Language tab of the {Some Language} > Color Coding node in Tools|Options, is that right?
I think you're saying that when "Color inactive code regions" is checked, and "Case-sensitive" is checked, then #if0..#endif are colored.
But that when "Color inactive code regions" is checked, and "Case-sensitive" is NOT checked, then #if0..#endif are NOT colored.
Is that an accurate understanding of what you're seeing?