If I have a lot of buffers loaded and (brief) hit Alt-B then hold down Alt-D (or just hit it rapidly) to delete a number of them then they disappear at a rate of 2 to 3 / sec. This isn't as bad as in the early betas, but it is a lot worse than B4 or SE17 where buffers could be killed at full auto-repeat. File tagging has also slowed down again, though again not to the same extent as in the early betas.
I should note that my files are nearly all C/C++ and mounted on network drives. (Win7 x64)